Diagenetiforms: A new term to explain protein changes as a result of diagenesis in paleoproteomics

The term proteoform describes all combinations of change in a protein, as elucidated through intact mass proteomics. Paleoproteomic studies have begun using digestion-free and top-down techniques to access information from ancient historical remains. However, discuss protein changes that uniquely occur archaeological paleontological proteomes the result diagenesis (i.e., physical chemical imparted by burial), novel is needed both addresses issues combinatorics distinguishes diagenetic-specific alteration. diagenetiform provides opportunity communicate clearly sets diagenetic found on preserved proteins. nomenclature will allow for paleoproteomic accurately describe total detected